A Statement of Intent to this effect has also been signed between the two countries in September.
Under the contract, the Qatar Emiri Air Force will receive 24 Typhoon aircraft, along with a bespoke support and training package.
Delivery of aircraft is expected to begin in late 2022.
UK Defence Secretary Gavin Williamson said: “These formidable jets will boost the Qatari military’s mission to tackle the challenges we both share in the Middle East, supporting stability in the region and delivering security at home.”
The aircraft will be assembled in the UK by BAE Systems, supporting thousands of jobs.
The deal also includes an agreement with MBDA for Brimstone and Meteor missiles and Raytheon’s Paveway IV UK-manufactured weapon for the jets.
Williamson has also agreed on a training and co-operation package between the airforces of both countries.
The deal includes the intention to proceed with the purchase of Hawk aircraft, the UK Ministry of Defence (MoD) stated.
The Typhoon contract follows a recent agreement signed by the Qatar Armed Forces to purchase an additional 12 Rafale multi-role fighter aircraft from Dassault Aviation.
The agreement will bring the total number of Rafale aircraft operated by the Qatar Emiri Air Force to 36.